The combination of Biostimulator injection and the PurpleLight System

The combination of Biostimulator injection and the PurpleLight System therapy for enhanced aesthetic rejuvenation outcome


Biostimulator injection therapy and the PurpleLight System are two innovative therapies that have gained popularity in recent years for aesthetic treatments. Biostimulator injections are used to promote healing and regeneration of tissues, while the PurpleLight System uses light therapy to improve the appearance of skin and reduce the signs of aging. In this white paper, we will explore the potential benefits of combining these two therapies for aesthetic treatments and how they can work together to enhance patient outcomes.


Biostimulator injections contain substances that when are injected into the target tissue they promote Collagen production. The injections are commonly used in aesthetic treatments to improve skin texture, reduce wrinkles, and enhance facial contours. The PurpleLight System uses a combination of blue, red, and infrared light to improve the appearance of skin and reduce the signs of aging. The therapy is non-invasive and has been used to treat a variety of skin conditions, including acne, rosacea, and hyperpigmentation.


Our protocol for the hybrid treatment of PurpleLight and biostimulator injection (RADIESSE®or Sculptra®) includes 6 sessions, one months apart:

Sessions 1-6: a PurpleLight System treatment that heats the tissue to the target temperature.

Sessions 1, 3: biostimulator injection after the cooling down of the tissue (about half an hour)– RADIESSE®- 1.5 cc of RADIESSE®+ (with lidocaine) diluted and mixed with 1.5 cc of saline, the mixture is injected to the face/neck 1.5 cc to each side.
Sculptra® – diluted according to the company's protocol and injected to the abdomen.

Benefits of combining biostimulator injection therapy with the PurpleLight System for aesthetic treatments:

  1. Improved skin texture: The combination of biostimulators and the PurpleLight System can enhance dramatically the production of collagen and elastin, leading to improved skin texture and elasticity.

  2. Reduced wrinkles: The PurpleLight System can help reduce the appearance of wrinkles and fine lines, while the biostimulators can promote collagen production to maintain the results up to 26 months.

  3. Enhanced facial contours: Biostimulator injections can be used to enhance facial contours, while the PurpleLight System can help reduce sagging and improve skin firmness.

  4. Non-invasive approach: The PurpleLight System is a non-invasive therapy, which means that patients can avoid the discomfort and potential risks associated with invasive cosmetic procedures. Biostimulator injections are minimally invasive and generally well-tolerated.

  5. Targeted treatment: The combination of biostimulator injections and the PurpleLight System can provide targeted treatment to specific areas of the face or body, leading to more precise and effective therapy.

  6. Synergistic effect: The use of both biostimulators and the PurpleLight System can have a synergistic effect, where the combined therapy is more effective than either treatment alone.


In conclusion, the combination of biostimulator injection therapy and the PurpleLight System can provide patients with improved skin texture, reduced wrinkles, enhanced facial contours, and a non-invasive approach for aesthetic treatments. This combined therapy is targeted, has a synergistic effect, and can lead to improved patient outcomes. While further research is needed to fully understand the benefits of this approach, early results are promising and suggest that this combined therapy could become an important tool in the field of aesthetic medicine

Dr. Orgil Matan MD

Plastic & Reconstructive Surgery Department 


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